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1

Proteomic Investigation of Metabolic Shift in Mammalian Cell Culture

Teck Keong Seow, Rashmi Korke, Rosa Cynthia Mui Yee Liang, Shao-En Ong, Keli Ou, Kathy Wong, Wei-Shou Hu, Maxey Ching Ming Chung

Journal:

Biotechnology Progress

Year:

2001

Language:

english

File:

PDF, 236 KB

english, 2001

2

A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling

Blagoev, Blagoy, Kratchmarova, Irina, Ong, Shao-En, Nielsen, Mogens, Foster, Leonard J., Mann, Matthias

Journal:

Nature Biotechnology

Year:

2003

Language:

english

File:

PDF, 1.03 MB

english, 2003

3

Identifying and quantifying in vivo methylation sites by heavy methyl SILAC

Ong, Shao-En, Mittler, Gerhard, Mann, Matthias

Journal:

Year:

2004

Language:

english

File:

PDF, 259 KB

english, 2004

4

A practical recipe for stable isotope labeling by amino acids in cell culture (SILAC)

Ong, Shao-En, Mann, Matthias

Journal:

Nature Protocols

Year:

2007

Language:

english

File:

PDF, 383 KB

english, 2007

5

Complementary RNA and protein profiling identifies iron as a key regulator of mitochondrial biogenesis

Jarred W. Rensvold, Shao-En Ong, Athavi Jeevananthan, Steven A. Carr, Vamsi K. Mootha, David J. Pagliarini

Journal:

Year:

2012

Language:

english

File:

PDF, 58 KB

english, 2012

6

Kinome chemoproteomics characterization of pyrrolo[3,4- c ]pyrazoles as potent and selective inhibitors of glycogen synthase kinase 3

Golkowski, Martin, Perera, Gayani K., Vidadala, Venkata Narayana, Ojo, Kayode K., Van Voorhis, Wesley C., Maly, Dustin J., Ong, Shao-En

Journal:

Molecular Omics

Year:

2018

Language:

english

File:

PDF, 3.47 MB

english, 2018

7

Two-dimensional electrophoresis map of the human hepatocellular carcinoma cell line, HCC-M, and identification of the separated proteins by mass spectrometry

Teck Keong Seow, Shao-En Ong, Rosa C. M. Y. Liang, Ee-Chee Ren, Lily Chan, Keli Ou, Maxey C. M. Chung

Journal:

ELECTROPHORESIS

Year:

2000

Language:

english

File:

PDF, 488 KB

english, 2000

8

Proteome analysis of a human heptocellular carcinoma cell line, HCC-M: An update

Keli Ou, Teck Keong Seow, Rosa C. M. Y. Liang, Shao-En Ong, Maxey C. M. Chung

Journal:

ELECTROPHORESIS

Year:

2001

Language:

english

File:

PDF, 199 KB

english, 2001

9

AAK1 Identified as an Inhibitor of Neuregulin-1/ErbB4-Dependent Neurotrophic Factor Signaling Using Integrative Chemical Genomics and Proteomics

Letian Kuai, Shao-En Ong, Jon M. Madison, Xiang Wang, Jeremy R. Duvall, Timothy A. Lewis, Catherine J. Luce, Sean D. Conner, David A. Pearlman, John L. Wood, Stuart L. Schreiber, Steven A. Carr, Edwar

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 1.47 MB

english, 2011

10

An evaluation of the use of two-dimensional gel electrophoresis in proteomics

Shao-En Ong, Akhilesh Pandey

Journal:

Biomolecular Engineering

Year:

2001

Language:

english

File:

PDF, 203 KB

english, 2001

11

Nucleolar proteome dynamics

Andersen, Jens S., Lam, Yun W., Leung, Anthony K. L., Ong, Shao-En, Lyon, Carol E., Lamond, Angus I., Mann, Matthias

Journal:

Year:

2005

Language:

english

File:

PDF, 465 KB

english, 2005

12

Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics

Blagoev, Blagoy, Ong, Shao-En, Kratchmarova, Irina, Mann, Matthias

Journal:

Nature Biotechnology

Year:

2004

Language:

english

File:

PDF, 329 KB

english, 2004

13

Mass spectrometry–based proteomics turns quantitative

Ong, Shao-En, Mann, Matthias

Journal:

Nature Chemical Biology

Year:

2005

Language:

english

File:

PDF, 354 KB

english, 2005

14

Proteomic screen defines the Polo-box domain interactome and identifies Rock2 as a Plk1 substrate

Lowery, Drew M, Clauser, Karl R, Hjerrild, Majbrit, Lim, Dan, Alexander, Jes, Kishi, Kazuhiro, Ong, Shao-En, Gammeltoft, Steen, Carr, Steven A, Yaffe, Michael B

Journal:

The EMBO Journal

Year:

2007

Language:

english

File:

PDF, 656 KB

english, 2007

15

Analysis of protein phosphorylation using mass spectrometry: deciphering the phosphoproteome

Matthias Mann, Shao-En Ong, Mads Grønborg, Hanno Steen, Ole N. Jensen, Akhilesh Pandey

Journal:

Trends in Biotechnology

Year:

2002

Language:

english

File:

PDF, 122 KB

english, 2002

16

Using mass spectrometry for drug discovery

Shao-En Ong, Akhilesh Pandey

Journal:

Trends in Biotechnology

Year:

2002

Language:

english

File:

PDF, 26 KB

english, 2002

17

JAK2 – not just another kinase

Shao-En Ong, Akhilesh Pandey

Journal:

Trends in Biochemical Sciences

Year:

2002

Language:

english

File:

PDF, 15 KB

english, 2002

18

Metabolomics Studies Show Dose-Dependent Toxicity Induced by SiO2 Nanoparticles in MRC-5 Human Fetal Lung Fibroblasts

Shao-Min Huang, Xinbing Zuo, Jasmine Jia'En Li, Sam Fong Yau Li, Boon Huat Bay, Choon Nam Ong

Journal:

Advanced Healthcare Materials

Year:

2012

Language:

english

File:

PDF, 1.19 MB

english, 2012

19

A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology

David J. Pagliarini, Sarah E. Calvo, Betty Chang, Sunil A. Sheth, Scott B. Vafai, Shao-En Ong, Geoffrey A. Walford, Canny Sugiana, Avihu Boneh, William K. Chen, David E. Hill, Marc Vidal, James G. Eva

Journal:

Year:

2008

Language:

english

File:

PDF, 1.89 MB

english, 2008

20

DNA Damage Activates a Spatially Distinct Late Cytoplasmic Cell-Cycle Checkpoint Network Controlled by MK2-Mediated RNA Stabilization

H. Christian Reinhardt, Pia Hasskamp, Ingolf Schmedding, Sandra Morandell, Marcel A.T.M. van Vugt, XiaoZhe Wang, Rune Linding, Shao-En Ong, David Weaver, Steven A. Carr, Michael B. Yaffe

Journal:

Year:

2010

Language:

english

File:

PDF, 1.74 MB

english, 2010

21

An integrated approach in the discovery and characterization of a novel nuclear protein over-expressed in liver and pancreatic tumors

Meng Ling Choong, Li Kiang Tan, Siaw Ling Lo, Ee-Chee Ren, Keli Ou, Shao-En Ong, Rosa C.M.Y. Liang, Teck Keong Seow, Maxey C.M. Chung

Journal:

Year:

2001

Language:

english

File:

PDF, 555 KB

english, 2001

22

AU Binding Proteins Recruit the Exosome to Degrade ARE-Containing mRNAs

Ching-Yi Chen, Roberto Gherzi, Shao-En Ong, Edward L. Chan, Reinout Raijmakers, Ger J.M. Pruijn, Georg Stoecklin, Christoph Moroni, Matthias Mann, Michael Karin

Journal:

Year:

2001

Language:

english

File:

PDF, 832 KB

english, 2001

23

Mass spectrometric-based approaches in quantitative proteomics

Shao-En Ong, Leonard J Foster, Matthias Mann

Journal:

Year:

2003

Language:

english

File:

PDF, 251 KB

english, 2003

24

Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach

Lee, Mark N, Roy, Matthew, Ong, Shao-En, Mertins, Philipp, Villani, Alexandra-Chloé, Li, Weibo, Dotiwala, Farokh, Sen, Jayita, Doench, John G, Orzalli, Megan H, Kramnik, Igor, Knipe, David M, Lieberma

Journal:

Nature Immunology

Year:

2012

Language:

english

File:

PDF, 1.05 MB

english, 2012

25

MSQuant, an Open Source Platform for Mass Spectrometry-Based Quantitative Proteomics

Mortensen, Peter, Gouw, Joost W., Olsen, Jesper V., Ong, Shao-En, Rigbolt, Kristoffer T. G., Bunkenborg, Jakob, Cox, Jürgen, Foster, Leonard J., Heck, Albert J. R., Blagoev, Blagoy, Andersen, Jens S.

Journal:

Journal of Proteome Research

Year:

2010

Language:

english

File:

PDF, 5.61 MB

english, 2010

26

The expanding field of SILAC

Journal:

Analytical and Bioanalytical Chemistry

Year:

2012

Language:

english

File:

PDF, 378 KB

english, 2012

27

Complementary RNA and Protein Profiling Identifies Iron as a Key Regulator of Mitochondrial Biogenesis

Rensvold, Jarred W., Ong, Shao-En, Jeevananthan, Athavi, Carr, Steven A., Mootha, Vamsi K., Pagliarini, David J.

Journal:

Year:

2013

Language:

english

File:

PDF, 977 KB

english, 2013

28

Phosphoproteomic Approach to Characterize Protein Mono- and Poly(ADP-ribosyl)ation Sites from Cells

Daniels, Casey M., Ong, Shao-En, Leung, Anthony K. L.

Journal:

Journal of Proteome Research

Year:

2014

Language:

english

File:

PDF, 11.56 MB

english, 2014

29

Properties of 13 C-Substituted Arginine in Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC)

Ong, Shao-En, Kratchmarova, Irina, Mann, Matthias

Journal:

Journal of Proteome Research

Year:

2003

Language:

english

File:

PDF, 206 KB

english, 2003

30

Comparing SILAC- and Stable Isotope Dimethyl-Labeling Approaches for Quantitative Proteomics

Lau, Ho-Tak, Suh, Hyong Won, Golkowski, Martin, Ong, Shao-En

Journal:

Journal of Proteome Research

Year:

2014

Language:

english

File:

PDF, 2.82 MB

english, 2014

31

Whole proteomes as internal standards in quantitative proteomics

Journal:

Genome Medicine

Year:

2010

Language:

english

File:

PDF, 375 KB

english, 2010

32

Huntingtin is associated with cytomatrix proteins at the presynaptic terminal

Yao, Jia, Ong, Shao-En, Bajjalieh, Sandra

Journal:

Molecular and Cellular Neuroscience

Year:

2014

Language:

english

File:

PDF, 764 KB

english, 2014

33

The Promise of Proteomics for the Study of ADP-Ribosylation

Daniels, Casey M., Ong, Shao-En, Leung, Anthony K.L.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.35 MB

english, 2015

34

A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G2/M DNA Damage Checkpoint

van Vugt, Marcel A. T. M., Gardino, Alexandra K., Linding, Rune, Ostheimer, Gerard J., Reinhardt, H. Christian, Ong, Shao-En, Tan, Chris S., Miao, Hua, Keezer, Susan M., Li, Jeijin, Pawson, Tony, Lewi

Journal:

Year:

2010

Language:

english

File:

PDF, 3.14 MB

english, 2010

35

Studying mechanisms of cAMP and cyclic nucleotide phosphodiesterase signaling in Leydig cell function with phosphoproteomics

Golkowski, Martin, Shimizu-Albergine, Masami, Suh, Hyong Won, Beavo, Joseph A., Ong, Shao-En

Journal:

Cellular Signalling

Year:

2015

Language:

english

File:

PDF, 2.44 MB

english, 2015

36

ENPP1 processes protein ADP-ribosylation in vitro

Palazzo, Luca, Daniels, Casey M., Nettleship, Joanne E., Rahman, Nahid, McPherson, Robert Lyle, Ong, Shao-En, Kato, Kazuki, Nureki, Osamu, Leung, Anthony K. L., Ahel, Ivan

Journal:

Year:

2016

Language:

english

File:

PDF, 2.19 MB

english, 2016

37

SCAP/SREBP pathway is required for the full steroidogenic response to cyclic AMP

Shimizu-Albergine, Masami, Van Yserloo, Brian, Golkowski, Martin G., Ong, Shao-En, Beavo, Joseph A., Bornfeldt, Karin E.

Journal:

Proceedings of the National Academy of Sciences

Year:

2016

Language:

english

File:

PDF, 1.89 MB

english, 2016

38

Clinical outcome of reflex EGFR mutation and ALK fusion testing in patients with non-squamous non-small cell lung cancer

Tan, Jonan Zhi-En, Ong, Whee-Sze, Tan, Daniel Shao-Weng, Takano, Angela, Lim, Tony Kiat-Hon, Chan, Kian-Sing, Oon, Lynette, Lim, Alvin Soon-Tiong, Lim, Tse-Hui, Jain, Amit, Toh, Chee-Keong, Ang, Mei-K

Journal:

Cancer Treatment and Research Communications

Year:

2016

Language:

english

File:

PDF, 305 KB

english, 2016

39

Encyclopedia of Life Sciences || Two-dimensional Gel Electrophoresis

Year:

2001

Language:

english

File:

PDF, 117 KB

english, 2001

40

Kinobead and Single-Shot LC-MS Profiling Identifies Selective PKD Inhibitors

Golkowski, Martin, Vidadala, Rama Subba Rao, Lombard, Chloe K., Suh, Hyong Won, Maly, Dustin J., Ong, Shao-En

Journal:

Journal of Proteome Research

Year:

2017

Language:

english

File:

PDF, 1.59 MB

english, 2017

41

ADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulence

McPherson, Robert Lyle, Abraham, Rachy, Sreekumar, Easwaran, Ong, Shao-En, Cheng, Shang-Jung, Baxter, Victoria K., Kistemaker, Hans A. V., Filippov, Dmitri V., Griffin, Diane E., Leung, Anthony K. L.

Journal:

Proceedings of the National Academy of Sciences

Year:

2017

Language:

english

File:

PDF, 794 KB

english, 2017

42

Nudix hydrolases degrade protein-conjugated ADP-ribose

Daniels, Casey M., Thirawatananond, Puchong, Ong, Shao-En, Gabelli, Sandra B., Leung, Anthony K. L.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 2.44 MB

english, 2016

43

Analyses of PDE-regulated phosphoproteomes reveal unique and specific cAMP-signaling modules in T cells

Beltejar, Michael-Claude G., Lau, Ho-Tak, Golkowski, Martin G., Ong, Shao-En, Beavo, Joseph A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2017

Language:

english

File:

PDF, 1.29 MB

english, 2017

44

Peroxiredoxin 6 mediates Gαi protein-coupled receptor inactivation by cJun kinase

Schattauer, Selena S., Land, Benjamin B., Reichard, Kathryn L., Abraham, Antony D., Burgeno, Lauren M., Kuhar, Jamie R., Phillips, Paul E. M., Ong, Shao En, Chavkin, Charles

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 2.40 MB

english, 2017

45

Noncanonical translation via deadenylated 3′ UTRs maintains primordial germ cells

Jin, Youngnam N., Schlueter, Peter J., Jurisch-Yaksi, Nathalie, Lam, Pui-Ying, Jin, Shan, Hwang, Woong Y., Yeh, Jing-Ruey Joanna, Yoshigi, Masaaki, Ong, Shao-En, Schenone, Monica, Hartigan, Christina

Journal:

Nature Chemical Biology

Year:

2018

Language:

english

File:

PDF, 1.92 MB

english, 2018

46

Crystal Structure of the COMPASS H3K4 Methyltransferase Catalytic Module

Hsu, Peter L., Li, Heng, Lau, Ho-Tak, Leonen, Calvin, Dhall, Abhinav, Ong, Shao-En, Chatterjee, Champak, Zheng, Ning

Journal:

Year:

2018

Language:

english

File:

PDF, 6.26 MB

english, 2018

47

Depletion of dAKAP1-protein kinase A signaling islands from the outer mitochondrial membrane alters breast cancer cell metabolism and motility

Aggarwal, Stacey, Gabrovsek, Laura, Langeberg, Lorene K, Golkowski, Martin, Ong, Shao-En, Smith, F Donelson, Scott, John D

Journal:

Journal of Biological Chemistry

Year:

2018

Language:

english

File:

PDF, 4.93 MB

english, 2018

48

5-HT 1B Receptor-Mediated Activation of ERK1/2 Requires Both Gα i/o and β-Arrestin Proteins

Liu, Yusha, Gibson, Alec W., Levinstein, Marjorie R., Lesiak, Atom J., Ong, Shao-En, Neumaier, John

Journal:

ACS Chemical Neuroscience

Year:

2019

File:

PDF, 1.41 MB

2019

49

5-HT 1B Receptor-Mediated Activation of ERK1/2 Requires Both Gα i/o and β-Arrestin Proteins

Liu, Yusha, Gibson, Alec W., Levinstein, Marjorie R., Lesiak, Atom J., Ong, Shao-En, Neumaier, John

Journal:

ACS Chemical Neuroscience

Year:

2019

Language:

english

File:

PDF, 1.41 MB

english, 2019

50

Ion-pairing with triethylammonium acetate improves solid-phase extraction of ADP-ribosylated peptides

McPherson, Robert Lyle, Ong, Shao-En, Leung, Anthony K.L.

Journal:

Journal of Proteome Research

Year:

2019

Language:

english

File:

PDF, 26.23 MB

english, 2019